Discover an up-to-date meta-analysis and trial sequential analysis (TSA) results that has been done by an independent external peer review, to provide an overview of the efficacy of Negative Pressure Wound Therapy (NPWT) vs standard dressings on the incidence of Surgical Site Infection (SSI) where 57 RCTs with 13 744 patients has been included.
Evidence in focus: Incisional negative pressure wound therapy for the prevention of surgical site infection: an up-to date meta-analysis and trial sequential analysis.
Groenen H, Jalalzadeh H, Buis DR, et al. eClinicalMedicine (part of the Lancet group). 2023;62;102105
+ Overview
+ Conclusion
This meta-analysis confidently showed that single use iNPWT reduces SSI irrespective of surgical specialty, whilst trial sequential analysis demonstrated the robustness of this evidence. Additionally, no significant differences were observed between -80mmHg and -125mmHg devices.
+ Our engagement
We are dedicated to supporting healthcare professionals in reducing the human and economic impacts of post-operative surgical site complications (SSCs).
The development of SSCs, such as surgical site infections (SSIs), oedema, seroma, haemotoma, or surgical wound dehiscence is a substantial burden for patients and healthcare systems globally.1
Discover how we are shaping what's possible in reducing the burden of surgical wound complications